Each film coated tablet contains:
Tenofovir Disoproxil Fumarate IP..300mg
Colours: Lake Indigo Carmine & Titanium Dioxide IP
Oral, Film coated tablet
Tenofovir disproxil fumarate is an acyclic nucleoside phosphatediester analog of adenosine monophosphate.Tenofovir disproxil fumarate requiresinitial diester hydrolysis for conversion to tenofovir and subsequentphosphorylations by cellular enzymes to form tenofovir diphosphate, an obligatechain terminator. Tenofovir diphosphate inhibits the activity of HIV-1 reversetranscriptase and HBV reverse transcriptase by competing with the naturalsubstrate deoxyadenosine 5-triphosphate and after incorporation into DNA chaintermination.
Dosage and administration:
For treatment of HIV-1 or chronic hepatitis B
The dose of TENVIR is 300 mg once daily taken orally,without regard to food. In the treatment of chronic hepatitis has not beenestablished.
Limited clinical experience at doses higher than thetherapeutic dose of tenofovir disoproxil fumarate 300 mg is available. In study901, 600 mg tenofovir disoproxil fumarate was administrated to 8 subjectsorally for 28 days. No severe adverse reactions were reported. The effects ofhigher doses are not known.
If overdose occurs the patient must be monitored forevidence of toxicity and standard supportive treatment applied as necessary.Tenofovir is efficiently removed by haemodialysis.
Medicine should be kept out of reach of children.
Do not use the medicine after expiry date.
Do not take medicine without doctorÃ¢ÂÂs consultance.
Take the right amount of dose of medicine as prescribed byyour doctor.
Notice: The information given here is for only foreducational aid only. Do not indulge yourself in self medication by followinginternet information. This could be dangerous for you.
Storage and Handling Instructions:
Store in cool and dry place.
Tenvir TabletsContainer pack of 30 Tablets.
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